Antitumorigenic Effects of Cannabinoids beyond Apoptosis

Research Subject: Cancer
Author: Nadine Freimuth, Robert Ramer and Burkhard Hinz
Publish Date: 2009

According to the World Health Organization, the cases of death caused by cancer will have been doubled until the year 2030. By 2010, cancer is expected to be the number one cause of death. Therefore, it is necessary to explore novel approaches for the treatment of cancer. Over past years, the antitumorigenic effects of cannabinoids have emerged as an exciting field in cancer research. Apart from their proapoptotic and antiproliferative action, recent research has shown that cannabinoids may likewise affect tumor cell angiogenesis, migration, invasion, adhesion, and metastasization. This review will summarize the data concerning the influence of cannabinoids on these locomotive processes beyond modulation of cancer cell apoptosis and proliferation. The findings discussed here provide a new perspective on the antitumorigenic potential of cannabinoids.

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  1. Peter Reynolds says:

    Again, all in vitro or in vivo (animal) studies even if using human cell lines implanted in animals.

    It is extremely far fetched, not to say irresponsible and misleading to suggest these results can be directly transferred to living, breathing human beings.

    Overstating the case for medicinal use of cannabis is unnecessary because there is very good evidence of its palliative benefits. Let’s wait for real clinical studies before giving people false hope.

  2. Valerie Swinfen says:

    Do you speak for the pharma companies Peter???

  3. MedicalMarijuanaMedicalMarijuana says:

    Peter, we have simply published a peer-reviewed scientific study, we haven’t suggested that this can be used on human beings, we are simply presenting the evidence verbatum.

  4. Steve Foster says:

    If medical “standard of care” had anything to offer that was effective, that would be another matter. But considering that the 5 yr survival of patients who undergo chemo is about 2.1%, I’ll take what you consider as “false hope” over no hope at all.

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