Marijuana, THC and Pulmonary Antibacterial Defenses
Research Subject: Antibacterial
Author: Gary Huber, Val Pochay, Wlademir Pereira et al.
Publish Date: 1980
Although marijuana is now consumed extensively, little is known of its biologic effects on the lung. To study this problem, the intrapulmonary inactivation of an aerosolized challenge of Staphylococcus aureus was quantified in rats exposed to graded amounts of fresh marijuana smoke. Controls inactivated 85.1 percent ± 0.3 percent of the bacteria six hours after inoculation.
Following an in vivo accumulative exposure to smoke from progressively increasing numbers of marijuana cigarettes for periods of ten minutes each hour for five consecutive hours, intrapulmonary bacterial inactivation was impaired in a dose-dependent manner.
Cannabidiol reverses the mCPP-induced increase in marble-burying behavior
Cannabidiol (CBD), one of the main components of Cannabis sp., presents clinical and preclinical anx…
Cannabidiol reverses MK-801-induced disruption of prepulse inhibition in mice
Cannabidiol, a nonpsychoactive constituent of the Cannabis sativa plant, has been reported to act as…
Cannabidiol Rescues Acute Hepatic Toxicity and Seizure Induced by Cocaine
Cocaine is a commonly abused illicit drug that causes significant morbidity and mortality. The most …
Cannabidiol Reduces Intestinal Inflammation through the Control of Neuroimmune Axis
Enteric glial cells (EGC) actively mediate acute and chronic inflammation in the gut; EGC proliferat…
Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation and ameliorates multiple sclerosis-like disease in C57BL/6 mice
Cannabis extracts and several cannabinoids have been shown to exert broad antiinflammatory activitie…