Marijuana, THC and Pulmonary Antibacterial Defenses

Research Subject: Antibacterial
Author: Gary Huber, Val Pochay, Wlademir Pereira et al.
Publish Date: 1980

Although marijuana is now consumed extensively, little is known of its biologic effects on the lung. To study this problem, the intrapulmonary inactivation of an aerosolized challenge of Staphylococcus aureus was quantified in rats exposed to graded amounts of fresh marijuana smoke. Controls inactivated 85.1 percent ± 0.3 percent of the bacteria six hours after inoculation.
Following an in vivo accumulative exposure to smoke from progressively increasing numbers of marijuana cigarettes for periods of ten minutes each hour for five consecutive hours, intrapulmonary bacterial inactivation was impaired in a dose-dependent manner.

Download PDF