Cannabidiol Reduces Aβ-Induced Neuroinflammation and Promotes Hippocampal Neurogenesis through PPARγ Involvement

Research Subject: Batten Disease
Author: Giuseppe Esposito, Caterina Scuderi, Marta Valenza et al.
Publish Date: 2011

This study was aimed at exploring whether CBD effects could be subordinate to its activity at PPARc, which has been recently indicated as its putative binding site. CBD actions on bamyloid-induced neurotoxicity in rat AD models, either in presence or absence of PPAR antagonists were investigated.

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