Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo

Research Subject: Prostate Cancer
Author: Luciano De Petrocellis, Alessia Ligresti, Aniello Schiano Moriello et al.
Publish Date: 2012

We tested pure cannabinoids and extracts from Cannabis strains enriched in particular cannabinoids (BDS), on AR-positive (LNCaP and 22RV1) and -negative (DU-145 and PC-3) cells, by evaluating cell viability (MTT test), cell cycle arrest and apoptosis induction, by FACS scans, caspase 3/7 assays, DNA fragmentation and TUNEL, and size of xenograft tumours induced by LNCaP and DU-145 cells.

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